General
The Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy at the LVR University Hospital Essen is committed to advancing translational research on the biological mechanisms of psychiatric illnesses in childhood and adolescence.
General
The causes of these sex and gender differences and their pathophysiological relevance as well as the consistent adaptions of prevention and therapy measures, are increasingly becoming the focus of current research activities.
General
Our team offers services for the diagnosis and treatment of growth disorders, pubertal disorders, and diabetes mellitus. We focus on rare conditions like Prader-Willi syndrome.
General
This study aims to improve our understanding of endocrine complications after transplantation and to optimize long-term care for transplant recipients.
Autoimmune Disorder
The ODSL (Ophthalmic Disease and Systemic Laboratory) investigates the molecular mechanisms, risk factors, and novel therapeutic approaches of Graves’ Orbitopathy (GO), an inflammatory eye disease that typically occurs in association with Graves’ disease.
Endocrine Organs
We examine specimens from the thyroid, parathyroid glands, adrenal glands, and neuroendocrine tumors. Using microscopic examination along with additional techniques—such as immunohistochemistry and molecular pathology—we are able to make precise diagnoses.
Endocrine Tumors
At our centre, we are deeply committed to continuously improving the diagnosis, treatment and long-term care of patients with neuroendocrine tumours (NET).
Hormonal Effect
Thyroid hormones (TH) are not only essential for normal brain development, but also influence the metabolism and function of nearly every cell in the body. To exert their function, TH require transporters, which are located in the cell membrane and mediate the cellular uptake and efflux of TH.
Hormonal Effect
In the Pediatric Neuroendocrinology Research Group, we investigate how hormones influence the developing brain of children and adolescents—especially during sensitive developmental periods such as puberty.
Hormonal Effect
We investigate the impact of a systemic and local hepatic TH action in acute and cholestatic liver disease.
Hormonal Effect
Our group strives to understand the mechanisms of TH action in neural development and function and how these processes are affected if central TH signaling is perturbed.
Hormonal Effect
Our group investigates the diverse actions of thyroid hormones (TH) and their receptors (TRs) α and β, with the goal of understanding the mechanisms of TH action and translating these insights into therapeutic strategies.
New Genetic Causes
Body weight regulation is a complex biological process that is shaped by an interplay of environmental and genetic factors.
New Technology
To optimise care inpatient care for patients with diabetes, we are investigating the introduction of a digitalized diabetes management into routine care.
Thyroid Cancer
Our “Thyroid Oncology Research Unit” at the CEM is dedicated to the comprehensive research and treatment of malignant thyroid diseases.
Rare Complex Disease
Approximately 70% to 80% of rare diseases have a genetic etiology. Significantly more than half of those affected show (initial) symptoms in childhood. Those affected often have global developmental delay or intellectual disability.